BIOL 5597: Immunotherapies of Cancer and Infectious Disease
Lecture - 4 credits
- Describes the basic principles and the current promises and disappointments with immunotherapies of cancer.
- Provides a historical overview of the main barriers between tumors and antitumor killer cells.
- The unifying focus of the lectures is the role of immunological and physiological negative regulators, i.e., “brakes” of anti-tumor immune response.
- A significant part of the course is dedicated to the retrospective evaluation of the last three decades of the immunological and biochemical studies that culminated in identification of the “chief of tumor defense operations,” i.e., a hypoxia-adenosinergic pathway in the tumor microenvironment.
Describes the basic principles and the current promises and disappointments with immunotherapies of cancer. Show more.